EVLab

Secretome, extracellular vesicles (EVs) and microRNAs represent a new frontier in biomedical research. By mediating intercellular communication and regulating tissue homeostasis, immune responses, disease progression, and tissue regeneration, these secretome-derived components provide valuable insights into both physiological and pathological processes. Their study offers significant opportunities for the discovery of novel biomarkers, the development of advanced clinical tools, and therapeutic strategies. Prof. Massimo Dominici and his research team are recognized pioneers in cell- and gene-based therapies, with more than 20 years of experience in human mesenchymal stromal cell (MSC) biology and clinical application. More recently, through several funded projects, the team has acquired significant expertise in the isolation and characterization of extracellular vesicle (EVs) from cell supernatants and biological fluids. These projects have substantially strengthened the team’s technological capabilities and the integration of new technological strategies into the University’s core facilities for next-generation cell-free therapies.

Principal Investigator:  Professor Massimo Dominici

 

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EVs Analysis Unit